The Mississippi Perinatal Quality Collaborative (MSPQC) is a statewide partnership that aims to promote evidence-based quality improvement initiatives at the hospital and community level to improve birth outcomes across Mississippi. MSPQC relies on collaborative data-driven projects to address specific drivers of maternal and neonatal morbidity and mortality.These projects are selected by participating members across the state, who work to develop, disseminate and successfully implement best practices in all clinical settings caring for mothers and infants. While working collaboratively, the MSPQC has three divisions: Neonatal, Obstetric and Family Public Health. The MSPQC was launched in November of 2014.

MSPQC is funded by a grant provided through the Mississippi State Department of Health.